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Tadalafil — illustrative product photographFDA-approved medication
FDA-approved medicationPrescription only

Tadalafil

Prescription — daily or as needed

A longer-acting PDE5 inhibitor, taken daily or as needed, prescribed after a cardiovascular review.

Not sold here as a standalone treatment

We don't dispense the tadalafil tablet itself. Tadalafil is one of the active ingredients a provider can choose inside Compounded ED Treatment — a troche or tablet prepared for you by a licensed compounding pharmacy in our clinical partner's network, which is not the approved tablet and is described honestly on its own page. This page stays because the daily-versus-as-needed question is worth understanding before any visit.

See the sexual health medications we offer

How it works

FDA-approved for erectile dysfunction. Prescribed by a licensed provider only if appropriate for you.

The same pathway as sildenafil — inhibiting PDE5 so cGMP persists and vessels stay relaxed — but tadalafil clears from the body more slowly. That's what makes a low daily dose possible, and why the as-needed version has a longer window. Arousal is still required either way. The approved tablet is also labeled for the urinary symptoms of an enlarged prostate, which is why a provider may ask about those.

The full mechanism

Who it’s for

A provider may consider it when

  • You'd rather not plan around timing — the daily option removes that
  • You want a longer window than sildenafil offers
  • Your cardiovascular history has been reviewed and is clear for it

Reasons it may not be prescribed

  • Anyone taking nitrates — the same absolute contraindication as sildenafil, and it lasts longer because the drug does
  • Recent cardiac events, unstable angina or uncontrolled blood pressure
  • Anyone on alpha-blockers or specific antivirals without a full medication review

These are the same checks your provider runs in the visit. If one applies, they will tell you plainly — and the medication portion of what you paid comes back automatically.

Important safety information

Headache, indigestion, back or muscle ache, flushing and nasal congestion are the common ones — back ache is more associated with tadalafil than with sildenafil. Seek emergency care for an erection lasting more than four hours, or sudden vision or hearing loss.

  • FDA prescribing information: Cialis (tadalafil) tablets — DailyMed, label revised 2026-06
  • PDE5 Inhibitors — StatPearls, NCBI Bookshelf, updated 2023 — nitrate co-administration contraindication

Complete safety information is provided during your visit and with every prescription. This page is a summary, not a substitute for your provider's advice.

Questions

Will I definitely be prescribed this?

Not this tablet — we don't dispense it. What a provider on this platform can prescribe is Compounded ED Treatment, which may contain tadalafil, and a consultation does not guarantee that either: your heart health and medications are reviewed first, and if it isn't safe the provider says so.

Daily or as-needed?

Daily suits people who don't want to think about timing; as-needed suits less frequent use. Your provider will recommend based on your health and how you'd actually use it.

Not sold here on its own.

A provider can talk through what we do offer, and be straight about what would actually help.