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FDA-approvedPrescription only
Acne Prescription (doxycycline, clindamycin, benzoyl peroxide)
Prescription — short course, topical and/or oral, as prescribed
A short, provider-directed course for inflammatory acne: benzoyl peroxide with a topical antibiotic, and an oral antibiotic only where a provider judges it warranted. Sent to a local pharmacy if prescribed.
FDA-approved for acne vulgaris — topical clindamycin and benzoyl peroxide for inflammatory acne, and doxycycline as adjunctive therapy in severe acne. Prescribed by a licensed provider only if appropriate for you.
From$99$32 consultation included, not refunded · medication paid at your pharmacy, if prescribed
Choose your plan
One-time
Price
$99for the provider visit — medication paid at your pharmacy, if prescribed
Includes your $32 provider consultation (non-refundable). If your provider decides treatment isn’t appropriate, the rest is refunded automatically.
- Picked up at a local pharmacy you choose. If prescribed, the medication itself is paid for at the pharmacy; the price here covers the provider visit.
- Your provider confirms the dose. If they start you on a lower step, we refund the difference; if they choose a higher one within the same plan, the price you paid stands.
Adding to cart books a provider visit. You pay the shown total; the provider decides; the medication portion comes back automatically if they say no.
Questions
Will I definitely be prescribed this?
No. A consultation does not guarantee a prescription — and with antibiotics, part of the provider's job is deciding whether one is appropriate at all. Doxycycline's own label says it should be used only for infections proven or strongly suspected to be bacterial, and the dermatology guideline asks providers to limit oral antibiotics and to pair any antibiotic with benzoyl peroxide. If the provider prescribes, the prescription is sent to a local pharmacy and you pay for the medication there; what you pay here is the consultation, whether or not a prescription follows.
Why won't the provider just prescribe the antibiotic on its own?
Because used alone, topical and oral antibiotics select for resistant bacteria on your skin and in your gut. The guideline's strong recommendation is to combine them with benzoyl peroxide, which kills bacteria by oxidation and to which resistance does not develop, and to keep oral courses short. A provider who declines an antibiotic is following that, not withholding care.
Isn't benzoyl peroxide available over the counter?
Yes, at several strengths. If that is all your provider recommends, they may simply tell you which to buy rather than write a prescription for it — the prescription-only parts of this package are the antibiotics.
How it works
Inflammatory acne needs three things at once: a plugged follicle, the bacterium Cutibacterium acnes multiplying inside it, and the immune response to that. Each medication here works on a different link in that chain, which is why guidelines pair them rather than pick one. Benzoyl peroxide is an oxidising agent — it releases oxygen into the follicle, where it is directly bactericidal and mildly keratolytic, and bacteria do not become resistant to it the way they do to antibiotics. Clindamycin binds the bacterial ribosome and stops the bacterium making protein; applied as a gel it lowers C. acnes counts at the follicle, and it is never meant to be used alone because resistance follows. Doxycycline, a tetracycline, also blocks bacterial protein synthesis and has an anti-inflammatory effect of its own; its label positions it as adjunctive therapy in severe acne, and the current dermatology guideline treats it as a limited course always paired with benzoyl peroxide and a topical. The provider's first decision is whether an antibiotic belongs in your plan at all — for mostly blackheads and whiteheads the answer is usually a retinoid instead.
The full mechanismA provider may consider it if
- Red, tender or pus-filled spots that over-the-counter benzoyl peroxide alone hasn't controlled
- You want a defined course with a stated end point, and a plan for what maintains the result afterwards
- You can commit to a topical routine and daily sun protection while on it
It won’t be prescribed if
- A known allergy to tetracyclines, to clindamycin or lincomycin, or to benzoyl peroxide — this is a hard stop
- Pregnancy, trying to become pregnant, or breastfeeding — doxycycline is a hard stop: tetracyclines cross the placenta and can permanently discolour developing teeth and slow fetal bone growth
- A history of colitis, regional enteritis, ulcerative colitis or antibiotic-associated diarrhoea — clindamycin is contraindicated, even as a gel
- Mostly blackheads and whiteheads with little inflammation — an antibiotic is the wrong tool and the provider will say so
These are the same checks your provider runs in the visit. If one applies, they will tell you plainly — and the medication portion of what you paid comes back automatically.
What to expect
After your visit
If prescribed, the prescription — one, two or all three medications, as your provider decides — is sent to a local pharmacy you choose and you pay for the medication there. What you paid here is the consultation.
Weeks 1–2
Dryness, peeling and redness from the benzoyl peroxide; if doxycycline is included, take it with a full glass of water and stay upright for a while afterwards, and expect to burn faster in the sun.
Weeks 4–12
Where response is honestly judged. An oral antibiotic is a limited course with a stop date your provider sets, not an open-ended prescription; the topicals are what usually continue.
Safety
Side effects, before you decide
Benzoyl peroxide: dryness, peeling, redness and burning, and it bleaches hair, towels and fabric. Topical clindamycin: dryness, oiliness, burning and itching; rarely, diarrhoea or colitis even from the gel — persistent or bloody diarrhoea means stop and contact a provider. Doxycycline: nausea, an exaggerated sunburn reaction, and irritation or ulceration of the oesophagus if taken lying down; a persistent headache with vision changes can signal raised pressure around the brain and needs prompt review; like all antibiotics it can cause C. difficile diarrhoea. Not for use in pregnancy or in children under eight.
- FDA prescribing information (DailyMed): doxycycline hyclate — indications, warnings, contraindications; revised 2025-09-30
- FDA prescribing information (DailyMed): clindamycin phosphate gel 1% — indications, contraindications, warnings, adverse reactions; revised 2026-02-25
- FDA prescribing information (DailyMed): clindamycin phosphate and benzoyl peroxide gel — indications, mechanism, warnings; revised 2023-07
- Reynolds RV, Yeung H, Cheng CE, et al. Guidelines of care for the management of acne vulgaris. J Am Acad Dermatol. 2024;90(5):1006.e1–1006.e30 — strong recommendations for benzoyl peroxide, topical retinoids, topical antibiotics and oral doxycycline; topical antibiotic monotherapy not recommended; good-practice statements to limit systemic antibiotics and combine them with benzoyl peroxide and other topicals
Complete safety information is provided during your visit and with every prescription. This page is a summary, not a substitute for your provider's advice.
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See whether acne prescription (doxycycline, clindamycin, benzoyl peroxide) is right for you.
A licensed provider reviews your visit and decides. You receive medication only if prescribed, and that portion of your payment is refunded automatically if they say no.