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Prescription onlyCompounded — not FDA-approved
Semaglutide
Prescription — weekly injection
A GLP-1 medication taken as a weekly injection, prescribed as part of a medical weight loss plan when a provider judges it appropriate.
Compounded semaglutide is not FDA-approved. FDA-approved semaglutide products exist under brand names; a compounded copy is a different thing.
We don't offer this
We do not provide compounded semaglutide. The FDA shortage that made compounded copies permissible ended in 2025, and a compounded copy of a commercially available medication cannot be lawfully advertised. This page is here because the mechanism is worth understanding — not as an offer. Where a GLP-1 is genuinely the right treatment, the FDA-approved branded products are the route, and a provider can discuss that with you.
See what we do offer for weight lossHow it works
What it actually does
Semaglutide resembles GLP-1, a hormone your intestine releases after eating that signals fullness to the brain and helps regulate insulin. Natural GLP-1 breaks down within minutes; semaglutide resists the enzyme that clears it, so the fullness signal keeps arriving between meals. It also slows how quickly the stomach empties — which is why smaller meals satisfy, and also why nausea is the most common side effect.
See the full mechanism, step by stepThe evidence
What the trials actually found
Published results, with what they were measured against. A number without a comparator isn't evidence — it's advertising.
14.9% mean body-weight reduction
vs 2.4% on placebo
Over 68 weeks at 2.4mg weekly, alongside lifestyle intervention, in adults with overweight or obesity without diabetes.
Wilding et al., STEP 1 trial, New England Journal of Medicine, 2021
Trial averages describe a study population, not a prediction for you. Your provider will be direct about what is realistic given your history — and results depend on continuing treatment.
A provider may consider it if
- You want a medical approach rather than another diet
- You're willing to check in with a provider as the dose is adjusted
- You understand this is a long-term treatment, not a short course
It won't be prescribed if
- Anyone with a personal or family history of medullary thyroid carcinoma, or MEN 2 syndrome — this is a hard stop
- Pregnancy, trying to become pregnant, or breastfeeding
- A history of pancreatitis, without careful provider review
- Type 1 diabetes, gastroparesis, or an active eating disorder without in-person care
These are the same checks the visit runs. If one applies, the visit will tell you plainly rather than take your money.
What to expect
Realistically, month by month
Weeks 1–4
The starting dose is deliberately low — low enough that it isn't expected to do much yet. It's there to let your gut adapt.
Months 1–4
Your provider steps the dose up gradually, checking how you're tolerating it at each stage. The ramp is the treatment, not a delay before it.
Ongoing
Dose and plan are revisited at check-ins. Stopping generally means the appetite effects stop too — this is managed as an ongoing condition.
Safety, stated up front
Side effects, before you decide
Nausea, vomiting, diarrhoea, constipation and reflux are the common ones, usually worst just after a dose increase. Serious but uncommon risks include pancreatitis, gallbladder problems and kidney injury from dehydration. Your provider goes through the full list before prescribing, and complete information comes with every prescription.
- FDA prescribing information: semaglutide
- Boxed warning: medullary thyroid carcinoma risk in rodents; contraindicated with personal or family history of MTC or MEN 2
Complete safety information is provided during your visit and with every prescription. This page is a summary, not a substitute for your provider's advice.
Questions
Asked honestly, answered honestly
Will I definitely be prescribed this?
No — and be wary of anyone who promises otherwise. A licensed provider reviews your health history and prescribes only if it's appropriate and safe for you. If it isn't, we'll tell you why.
Is this the same as the brand-name versions?
Semaglutide is the medication itself; brand names are specific manufacturers' products. What your provider prescribes, and in what form, is a clinical decision we don't make on a marketing page.
What happens if I stop?
The mechanism stops with it — the fullness signalling returns to baseline. That's worth planning for with your provider rather than discovering.
Also for weight loss
We don't prescribe this — but the conversation is still worth having
A provider can talk through what we do offer for weight loss, and be straight with you about what would actually help.