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Prescription onlyCompounded — not FDA-approved
Sermorelin
Compounded — nightly injection
A peptide that prompts your own pituitary to release growth hormone in its natural rhythm — prescribed for recovery and body-composition goals when appropriate.
Compounded. Sermorelin was an FDA-approved product (Geref) later withdrawn for commercial — not safety — reasons, which is what makes compounding it lawful today.
Adding to your plan doesn't order anything and doesn't charge you — it tells the provider what you're hoping to discuss.
About 5 minutes. A licensed provider reviews your health and prescribes sermorelin only if it's right for you — there is no checkout here, and that's deliberate.
How it works
What it actually does
Sermorelin is a synthetic version of the first 29 amino acids of growth-hormone-releasing hormone (GHRH) — the fragment that carries its full activity. It signals the pituitary to release your own growth hormone, in your own pulsatile rhythm, subject to your body's own feedback loops. That feedback is the key difference from injecting growth hormone itself: your pituitary can still say no, which is why providers consider its safety profile more forgiving.
See the full mechanism, step by stepA provider may consider it if
- Recovery, sleep quality and body composition are your goals
- You want to work with your own hormone axis rather than override it
- You can commit to nightly dosing — release is naturally highest during sleep
It won't be prescribed if
- Active cancer, or a history of it, without your oncologist involved — growth signaling is not something to add casually
- Untreated thyroid or adrenal conditions, which blunt the axis it works through
- Anyone expecting bodybuilder-forum results — this is the conservative tool, and that's the point
These are the same checks the visit runs. If one applies, the visit will tell you plainly rather than take your money.
What to expect
Realistically, month by month
Weeks 1–4
Sleep quality is typically the first thing people notice, consistent with when growth hormone naturally releases.
Months 2–3
Where recovery and composition changes are honestly assessed — anything faster is water and wishful thinking.
Safety, stated up front
Side effects, before you decide
Injection-site reactions are the common ones. Flushing, headache and dizziness are reported. Because it raises growth hormone through your own pituitary, the excess-GH risks of direct hormone injection are lower — but screening still matters, which is why a provider reviews your history first.
- FDA drug listing history: sermorelin acetate (Geref) — approval and non-safety withdrawal
Complete safety information is provided during your visit and with every prescription. This page is a summary, not a substitute for your provider's advice.
Questions
Asked honestly, answered honestly
Is this the same as taking HGH?
No — and the difference matters. Injected growth hormone overrides your body's feedback loops; sermorelin asks your pituitary to do the releasing, and your own regulation stays in charge. That's why it's the version a cautious provider reaches for.
See whether sermorelin is right for you
Five minutes of questions, reviewed by a licensed provider. Treatment only if it's appropriate — and a straight answer either way.